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Writer's pictureGursimar Dhaliwal

Otto Warburg on cancer

Updated: Nov 1, 2021



Warburg investigated the metabolism of tumors and the respiration of cells, particularly cancer cells, and in 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme".


The hypothesis was postulated by the Nobel laureate Otto Heinrich Warburg in 1924. He hypothesized that cancer, malignant growth, and tumor growth are caused by the fact that tumor cells mainly generate energy (as e.g., adenosine triphosphate / ATP) by non-oxidative breakdown of glucose (a process called glycolysis

  • Otto Warburg is one of the greatest biochemists of all time.


  • Otto Warburg unveiled the first tumor-specific metabolic phenotype.


  • Tumor cells rely heavily on fermentation for the generation of metabolic.


  • The discovery of the Warburg effect was not accidental.


  • Otto Warburg developed biochemical manometry and the tissue slice technique.

Some of the key finding from Dr. Otto Warburg related to cancer that I will be using in my research are as follows:


  • No disease including cancer can survive in a alkaline environment

  • Cancer grows in oxygen deprived ACIDIC cells

  • Cancerous cells/tissues are ACIDIC while normal cells are ALKALINE

  • Remove at least 35% of oxygen content of a cell it MIGHT become cancerous

  • Dr. Warburg has made it clear that the root cause of cancer is oxygen deficiency, which creates an acidic state in the human body. Dr. Warburg also discovered that cancer cells are anaerobic (do not breathe oxygen) and cannot survive in the presence of high levels of oxygen, as found in an alkaline state.

  • All forms of cancer are characterized by hypoxia and acidosis


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