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What design patterns would you apply to this
I have an org.springframework.jdbc.datasource.SingleConnectionDataSource. It has an internal pool of connections. As it has the pool it would make sense to not go through the trouble of creating an instance of SqlConnection every time I need it. So my question is how would I implement SqlSessionFactoryBean, SqlTransactionManager and SqlDataSource (or what else) such that these are pooled.
"This" is a bit vague. What project are you using the SqlSessionFactoryBean? This is for the Spring framework, which Spring's documentation on DataSourceIntegration provides information on several of the things you're asking about.
You could implement your own SqlSessionFactoryBean and have it pool the connections automatically. However, I'd recommend that you use Spring's implementation for the following reasons:
Auto-grows (based on an ActiveSqlConnectionFactory bean)
Stores the connections in a non-configurable data source
Intended to only be used for transactions
Other patterns available would be Event sourced or CachingDataSource, but I'd recommend not doing those and implementing your own SqlSessionFactoryBean instead.
Edit: As you mentioned in your comment, your SqlSessionFactoryBean is in fact configured in the Spring configuration file. So, Spring is managing the databases and a connection pool.
In vivo investigation of an adenoviral vector encoding the VP1 gene of a dominant surface antigen of encephalomyocarditis virus after intracerebral application.
Protective immunity is one of the most important factors which should be considered in the development of a viral vaccine. In recent years, much attention has been paid to the dominant surface antigen of encephalomyocarditis virus (EMC) due to its ability to raise virus-specific neutralizing antibodies and to stimulate T helper cells. In this study, an adenoviral vector containing the EMC virus VP1 gene was constructed to identify the potential of the VP1 gene as a vaccine candidate. Using the xylazine/ketamine combination, 4-week-old BALB/c mice were 0b46394aab